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Turkish Journal of Fisheries and Aquatic Sciences 2020, Vol 20, Num, 3     (Pages: 229-233)

Localized Amyloid-like Accumulation in a Zebrafish (Danio rerio): A Case Report

Aykut Ulucan 1 ,Hayati Yuksel 2

1 Bingöl University, Vocational School of Health Services, Department of Medical Services and Techniques, 12000, Bingöl, Turkey
2 Bingöl University, Faculty of Veterinary, Medicine Department of Pathology, 12000, Bingöl, Turkey
DOI : 10.4194/1303-2712-v20_3_07 Viewed : 2535 - Downloaded : 2395 Amyloidosis is described as collection of extracellular proteins with a characteristic fibrillar form with electron microscopy, a typical X-ray diffraction pattern and a green reflection with Congo red affinity. Zebrafish is an appropriate model organism for studying developmental immunology for modeling many infectious disorders. We observed that localized amyloid-like deposition was in the peritoneal membrane which is showing greenish reflection in the polarized filter with Congo red staining and immuno-positive staining with primary antibody of amyloid precursor protein. Consequently, in this case report, we demonstrated that incidentally detected and rarely seen localized amyloid-like accumulation in a zebrafish. Keywords : Amyloid, Amyloidosis, Peritoneal, Immunohistochemistry, Histopathology