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¹ Islamic Azad University, Department of Fisheries, Azadshahr Branch, Azadshahr, Iran DOI : 10.4194/1303-2712-v19_9_06 Viewed : 4871 - Downloaded : 3595 This research was conducted to evaluate the partial replacement of plant sources by date waste meal (DWM) on growth, hematological and resistance of common carp. A total of 168 common carp fingerling (2.44±0.02 g) were randomly assigned to four groups in triplicate and fed for 12 weeks with substitution of plant sources by 5%, 10% and 15% of DWM and control diet. Some growth and feed utilization parameters including WG, SGR, CF, PER and LER were improved in group fed with 10% DWM; but, there were no significant differences (P>0.05) in growth and feeding parameters between different groups. The results showed that replacement of plant sources by DWM in diets did not affect MCV, MCH and all biochemical parameters while the fish treated with 15% WDM exhibited significantly decrease in RBC, Hb and neutrophil compare to the control and other groups (P<0.05). In addition, there were no significant differences (P>0.05) of Hct, MCV, MCH and all biochemical parameters between treatment groups. Resistance rate to acidy and thermal-salinity stress increased significantly in 5% DWM and control group (P<0.05), respectively. The present study indicates that DWM may be included up to 10% as a substitute for plant sources in common carp diet. Keywords : Common carp (Cyprinus carpio), Date (Phoneix dactylifera), Growth Hematology, Stress