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¹ Faculty of Fisheries, University of Istanbul, Ordu Cad. No: 200, 34470 Laleli, Istanbul, Turkey Viewed : 4362 - Downloaded : 4240 This study determined the factors affecting the breakout of vibriosis, a bacterial infection in sea bream reared in farms in the Aegean Sea coast of Turkey, particularly the Bodrum peninsula and in Çanakkale. Bacteriological diagnostic methods were applied to 60 juveniles and older fish obtained from 15 farms. Six isolates were identified as three Vibrio sp. according to the cell morphology, Gram-stain reaction, colony morphology, metabolic reactions and cell motility. Thus, the bacterial epizootic was diagnosed as. Factors such as transport stress, water temperature changes (rise or fall), handling, and low oxygen induced vibriosis among sea bream in farms along the Aegean Sea. Keywords : gilt-head sea bream, Sparus aurata, fish diseases, vibriosis, Aegean Sea